Dr. Lisa K. Jennings,

Dr. Lisa K. Jennings is a tenured Professor of Medicine at the University of Tennessee Health Science Center (UTCHS) in Memphis, Tennessee, USA. She has secondary appointments at the rank of Professor in the Departments of Molecular Sciences and Surgery as well as in the Joint Program of Biomedical Engineering at UTHSC and the University of Memphis. Dr. Jennings attended graduate school at UTHSC and completed her Ph.D. thesis research at St. Jude Children's Research Hospital and the Gladstone Foundation Laboratories in San Francisco. She completed a post-doctoral fellowship at St. Jude Children's Research Hospital where she was a Leon Journey Fellow, and was appointed to the faculty of UTCHS in 1985.

Dr. Jennings is Director of the UTCHS Vascular Biology Center of Excellence (www.utmem.edu/vascular) and of the TN-AR-MS (TAM) Clinical Research Consortium. Dr. Jennings has an established research program in the area of platelet biology, specifically the function of surface membrane receptors and associated signaling pathways. She has primarily focused on the biology of the GPIIb-IIIa receptor as well as the tetraspanin CD9. She has expertise in the study and evaluation of antiplatelet and antithrombin agents including the design and conduct of the pharmacodynamic assessment of these agents in pre-clinical studies and in clinical trials. Clinical trials include IMPACT, IMPACT II, PRIDE, ESPRIT, and PROTECT trials of eptifibatide (Integrilin), PYRAMID (YM337), ORATOR, TIMI15A and B (Klerval), PICOLO (clopidogrel) and TAM 1 and TAM 2 trials (Integrilin vs. Aggrastat or ReoPro).

In addition, her research interests focus on the release of platelet mediated inflammatory proteins. Other research efforts in the Vascular Biology Center concentrate on vascular injury response, particularly signaling pathways associated with smooth muscle migration and proliferation and restenosis. Dr. Jennings has more than 60 publications in peer-reviewed journals and 100 abstracts. She has received grant support by the NIH, the American Heart Association or industry since 1983.